GHRH And Sermorelin

GHRH has been show to have a potent effect on brain function, decreasing the likelihood of Alzheimer’s and even improving cognition in adults.

Growth hormone releasing hormone triggers the release of growth hormone, which in turn triggers the release of IGF1, which is responsible for the beneficial effects of GH replacement therapy. However, GHRH seems to have important benefits of its own, particularly in adults.

A 2012 study at the University of Washington School of Medicine found that GHRH, growth hormone, and IGF1 play a role in the development of Alzheimer’s as levels of these hormones decline. The short-term administration (20 weeks) of HGH improved cognition in older adults and suggest that same would be true in adults with mild cognitive impairment.

What Is GHRH And What Does It Do?

GHRH is produced by the hypothalamus in the brain, along with thyroid releasing hormone, cortisol releasing hormone, and luteinizing hormone (LH, sometimes GHRH).

The role of GHRH is to stimulate the production of growth hormone by the pituitary.

The action of GHRH is opposed by somatostatin, which is also secreted by the hypothalamus. The on again, off again pulses of GHRH and somatostatin controls the pulses of growth hormone.

Is GHRH Available In Prescription Form?

There is no bioidentical form of GHRH. Most drugs are currently in the research stages and cannot be obtained.  However, some manufacturers have made drugs which contain shorter sequences of the 44 amino acids found in natural GHRH.

Sermorelin (Geref)

Geref, or sermorelin acetate, is made by Serono, which also produces prescription growth hormone. Considerably less expensive than growth hormone, sermorelin was introduced to the market in 1990 for use in children.  It was withdrawn by the manufacturer recently, not for health or safety reasons, but in order to relaunch the product.

Sermorelin is the shortest functional fragment of GHRH. It is sometimes called GRF-29 because it contains 29 amino acids out of the 44 found in natural GHRH. It has been widely used as a test for growth hormone production, but is now becoming used for its own sake in hormone replacement therapy.

The advantages of sermorelin are several.  First, it triggers the body to produce its own growth hormone. Second, the cost is less. Third, it works well with testosterone. And finally, there is evidence that longterm sermorelin therapy can be stopped and the benefits of high growth hormone levels will remain.

Other GHRH-Type Secretagogues

    • Tesamorelin Acetate (Egrifta) – Discontinued
    • CJC-1295 (ConjChem) –
    • CJC-1293
    • GHRP-6
    • Hexarelin
    • HRF-129 (Semorelin)
    • Somatoliberin
    • Somatocrinin
    • Pralmorelin (GHRP-2)
    • Nuvision Pharmacy has recalled its Sermorelin/GHRH and HCG formulations due to quality control issues and possible contamination.

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HGH Therapy is under the umbrella of AAG Health and Wellness, the world leaders in hormone management for adults. As the pioneers in treating adult hormone deficiencies to achieve optimal wellness, we are uniquely qualified to help adults of all ages regain a rich, fuller, and more satisfying quality of life. To find out if you are a candidate for growth hormone replacement therapy, please call us at 888-877-4206 or complete the contact form and a representative will get back to you.

What Is GHRH And What Does It Do?

GHRH is produced by the hypothalamus in the brain, along with thyroid releasing hormone, cortisol releasing hormone, and luteinizing hormone (LH, sometimes GHRH).

The role of GHRH is to stimulate the production of growth hormone by the pituitary.

The action of GHRH is opposed by somatostatin, which is also secreted by the hypothalamus. The on again, off again pulses of GHRH and somatostatin controls the pulses of growth hormone.

Is GHRH Available In Prescription Form?

There is no bioidentical form of GHRH. Most drugs are currently in the research stages and cannot be obtained.  However, some manufacturers have made drugs which contain shorter sequences of the 44 amino acids found in natural GHRH.

Sermorelin (Geref)

Geref, or sermorelin acetate, is made by Serono, which also produces prescription growth hormone. Considerably less expensive than growth hormone, sermorelin was introduced to the market in 1990 for use in children.  It was withdrawn by the manufacturer recently, not for health or safety reasons, but in order to relaunch the product.

Sermorelin is the shortest functional fragment of GHRH. It is sometimes called GRF-29 because it contains 29 amino acids out of the 44 found in natural GHRH. It has been widely used as a test for growth hormone production, but is now becoming used for its own sake in hormone replacement therapy.

The advantages of sermorelin are several.  First, it triggers the body to produce its own growth hormone. Second, the cost is less. Third, it works well with testosterone. And finally, there is evidence that longterm sermorelin therapy can be stopped and the benefits of high growth hormone levels will remain.

Other GHRH-Type Secretagogues

Tesamorelin Acetate (Egrifta) – Discontinued
CJC-1295 (ConjChem) –
CJC-1293
GHRP-6
Hexarelin
HRF-129 (Semorelin)
Somatoliberin
Somatocrinin
Pralmorelin (GHRP-2)
Nuvision Pharmacy has recalled its Sermorelin/GHRH and HCG formulations due to quality control issues and possible contamination.

HGH Therapy is under the umbrella of AAG Health and Wellness, the world leaders in hormone management for adults. As the pioneers in treating adult hormone deficiencies to achieve optimal wellness, we are uniquely qualified to help adults of all ages regain a rich, fuller, and more satisfying quality of life. To find out if you are a candidate for growth hormone replacement therapy, please call us at 888-877-4206 or complete the contact form and a representative will get back to you.

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