HGH And Low T (Andropause)

The symptoms of low T are very similar to growth hormone deficiency. Testosterone works hand in hand with growth hormone to build muscle, increase energy and stamina, and maintain a normal, healthy sex drive.

By age 40, most men are experiencing a substantial decrease in both growth hormone and testosterone. To be truly effective, growth hormone replacement should be in balance with other hormones, especially testosterone. Many clinics fail to treat low testosterone in addition to low growth hormone.

Further, an imbalance or deficiency in one hormone has a domino effect, causing imbalances in other hormones such as cortisol and thyroid, creating the cumulative effect seen in aging.

By the time men enter their 50s and the beginnings of andropause, or male menopause, most men are suffering from a combination of hormone and nutrient deficiencies, ranging from low testosterone and growth hormone to minerals such as zinc. Many are suffering from adrenal fatigue, due to chronically high levels of cortisol (the stress hormone). Thyroid functioning may also be impaired, leading to lethargy and metabolic weight gain.

Deficiencies in the 3 primary hormonal axises (growth hormone, testosterone, and cortisol) are all associated with aging, decreased functioning, and loss of wellbeing. In order to restore optimal functioning, all of these hormones should be considered in hormone replacement therapy.

The sequencing of hormone replacement therapy is important. Adrenal fatigue, for example, is magnified by high levels of growth hormone. For this reason, adrenal fatigue is often treated before HGH therapy is begun. Thyroid hormone functioning is generally restored at the same time as growth hormone, because growth hormone and thyroid hormone work together to enhance metabolic functioning.

The symptoms of andropause (male menopause) include low energy, loss of libido (sex drive), erectile dysfunction, depression and irritability, muscle loss and loss of strength, decreased endurance, weight gain (particularly around the abdomen), difficulty sleeping and insomnia.

Andropause and Low Growth Hormone


In a study of 333 patients with low growth hormone, these patients were twice as likely to die from heart disease as patients in the control group.

-Dr. Bengt-Ake Bengtsson, 1996 Anti-Aging Conference in Las Vegas, Nevada

Human growth hormone (HGH) is produced by the pituitary gland and declines with age. HGH is considered a “master hormone” because its presence regulates the secretion of other hormones, affecting all the cells in the body. Sleep, exercise, and certain other hormones and amino acids will increase the secretion of HGH. Stress will also cause a temporary spike in growth hormone production. Symptoms of low HGH include fatigue, low libido, weight gain )especially around the abdomen), joint and muscle pain, decreased mental acuity and memory, decreased strength and endurance, loss of muscle mass and bone density, skin aging (dryness and thinning, and increased risk of heart disease and strokes. HGH therapy is designed to boost IGF-1, which is responsible for many of the growth (anabolic) effects associated with growth hormone. HGH therapy will try to push IGF-1 levels to the upper ranges of normal. Treatment requires the injection of growth hormone anywhere between 3 and 6 days a week.  Using recombinant DNA technology, two forms of synthetic HGH have been created: somatropin and somatrem. Somatropin is identical to the endogenous pituitary-derived hGH, whereas somatrem has an extra amino acid. Both synthetic forms have similar biological actions and potencies as naturally-produced HGH. Synthetic HGH is chemically indistinguishable from the naturally occurring hormone in blood and urine tests. Prescription HGH is administered by injection. Adult dosages are  from 0.9-25 microgram/kilogram/day, dependent on the level of deficiency and the product. The FDA-approved injectable formulations are available as liquid preparations and as powder with a diluent for reconstitution, but both are fragile and require care with storage and use. Frequent and longterm injection cycles are required, because the circulating half-life of HGH is short (20-30 minutes) while its influence upon other hormones and cells in the body (biological half-life) is between 9 and 17 hours.

Andropause and Low Testosterone

Testosterone is produced by the Leydig cells in the testicles and is secreted in the blood stream, traveling to all cells in the body. Like many other important hormones, testosterone decreases as men age. Symptoms of low testosterone (low T) include a decrease in libido (sex drive), erectile dysfunction, memory loss, loss of muscle and bone density, weight gain, and depression. Testosterone replacement therapy requires the use of bioidentical hormones administered under medical supervision. While testosterone replacement products are available in gels and patches, the most effective treatment for low T is injectable testosterone.

Andropause and Low Thyroid

An underactive thyroid gland is a common condition in men, and subclinical low thyroid is difficult to diagnose. Low thyroid (hypothyroidism) causes fatigue along with hair loss, weight gain, constipation, cold sensitivity, memory loss and “brain fog,” and dry skin. It is also linked to the chronic muscle and joint pain of fibromyalgia in men. It is estimated that that between 30% and 80% of the population suffers from some degree of hypothyroidism.  Treatment for hypothyroidism includes bioidentical hormone replacement, such aa Armor Thyroid, which contains the active thyroid hormones free tyroxine (T4) and free tri-iodothyronine (T3). Thyroid stimulating hormone (TSH) is produced by the pituitary gland, which also produces growth hormone.

Andropause and Low Cortisol

Cortisol (stress hormone) is produced by the adrenal glands, which sit on top of the kidneys. When cortisol levels rise in response to stress, men get a boost of energy, memory is improved, and motivation increases. However, when stress levels are prolonged, cortisol remains elevated, causing toxic effects. These include depression, memory loss, fatigue, stomach ulcers, weight gain and food cravings, bone density loss (osteoporosis), loss of immune function, high blood pressure and elevated cholesterol. Chronically high cortisol leads to the collapse of adrenal gland functioning, or “adrenal fatigue.” The symptoms of this are manifest in poor glucose regulation and weight gain, rheumatoid arthritis, heart disease, insomnia, asthma and the onset of allergies, muscles aches and pains, depression, and stress intolerance. These symptoms are usually seen in older men who are experiencing andropause. The treatment for adrenal fatigue (low cortisol) is replacement therapy using bioidentical cortisol.

Andropause and Low DHEA

Dehydroepiandrosterone (DHEA) is s steroid hormone synthesized from cholesterol by the adrenal glands, which also regulate cortisol production. The amount of DHEA produced by men decreases with age, and by age 70 men produce only 20% of the DHEA they had when they were in their 20s. DHEA is called the “mother hormone”  and the “feel good hormone” because it is a precursor to the major sex hormones, including testosterone. If the adrenals glands have pumped out too much cortisol, adrenal fatigue results and the body can no longer produce adequate levels of DHEA. This is associated with extreme fatigue, inability to cope with stress, and depression. Low levels of DHEA make it impossible for the endocrine system to function, throwing off hormone balances, and creating a broad range of symptoms seen in andropause. Healthy levels of DHEA may help fight off Alzheimer’s, osteoporosis, cancer, depression, heart disease, and obesity.

Andropause and Low Melatonin

Melatonin is a hormone produce by the pineal gland deep inside the brain. It is triggered by circadian rhythms (sunlight and darkness). Melatonin levels begin to rise in the evening and reach their peak around midnight, when HGH production is at its height. Melatonin is required for deep sleep and deficiency will  interfere with the production of growth hormone. Melatonin may also help slow down aging in the body and the brain. It supports the immune system and provides a defense against autoimmune system malfunctioning and associated infections as well as cancer. Replacement in sublingual form (about .1 milligrams before going to bed) improves sleep quality and provides powerful antioxidant properties.

HGH Therapy is under the umbrella of AAG Health and Wellness, the world leaders in hormone management for adults. As the pioneers in treating adult hormone deficiencies to achieve optimal wellness, we are uniquely qualified to help adults of all ages regain a rich, fuller, and more satisfying quality of life. To find out if you are a candidate for growth hormone replacement therapy, please call us at (866)-977-5816 or complete the contact form and a representative will get back to you.

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