HGH has important clinical benefits for the brain, including cognition and memory. It improves mood and outlook. It promotes longer, deeper, and more restful sleep. It also mitigates anxiety and depression.

Psychological Benefits

McGauley, G.A. (Department of Medicine, United Medical and Dental Schools of Guy’s and St Thomas’s Hospitals, St Thomas’s Hospital, London, UK). Quality of life assessment before and after growth hormone treatment in adults with growth hormone deficiency. Acta Paediatr Scand [Suppl] 356: 70, 1989.
…patients with GHD may be psychologically compromised. Preliminary analysis of the results shows that after 6 months patients receiving human growth hormone (hGH) treatment experienced less perceived illness than the placebo group. Significant psychological improvement was noted in the hGH-treated patients’ perception of their energy level and mood compared to the placebo group.

Psychological Well-Being before and after Growth Hormone Treatment in Adults with Growth Hormone Deficiency
McGauley G.A. · Cuneo R.C. · Salomon F. · Sönksen P.H.
Horm Res 1990;33:52–54 (DOI: 10.1159/000181584)

Growth Hormone Deficiency and Quality of Life
McGauley G. · Cuneo R. · Salomon F. · Sönksen P.H.
Horm Res 1996;45:34–37 (DOI: 10.1159/000184756)
The majority of studies investigating the effects of growth hormone replacement therapy indicate that quality of life improves with treatment, although this is not a consistent finding.

McGauley, G.A. (Department of Medicine, United Medical and Dental Schools of Guy’s and St Thomas’s Hospitals, St Thomas’s Hospital, London, UK). Quality of life assessment before and after growth hormone treatment in adults with growth hormone deficiency. Acta Paediatr Scand [Suppl] 356: 70, 1989.

Cognitive Improvement

Clinical Trials Underway As Of 2009 on GH and Cerebral Metabolism, Stanford U. and Genentech

Summary of Benefits of GH on Cognition


Baker LD, Barsness SM, Borson S, Merriam GR, Friedman SD, Craft S, Vitiello
MV. Effects of growth hormone–releasing hormone on cognitive function in adults
with mild cognitive impairment and healthy older adults: results of a controlled
trial. Arch Neurol. 2012 Nov;69(11):1420-9. PubMed PMID: 22869065; PubMed Central
PMCID: PMC3764914.

Effects of growth hormone replacement on cognition after traumatic brain injury Neurotrauma. 2010 September; 27(9): 1565–1575.
doi: 10.1089/neu.2009.1253
PMCID: PMC2966848

For many years, investigators have assumed that all of the cognitive impairments in executive functioning, information-processing speed, and memory, were due solely to diffuse axonal injury and structural focal injuries to the frontal and temporal lobes. The findings from this study and from other recent studies indicate that in a significant proportion of persons with moderate to severe TBI, some of the observed cognitive impairments may actually be the result of GH deficiency, and could potentially be partially reversible with GH replacement therapy. Furthermore, there is the intriguing possibility that the effects of GH replacement may be partially use-dependent, raising the possibility that the effects of GH replacement may be maximized in the context of vigorous rehabilitation.


GHRH Hormone Improves Cognition In Healthy Older Adults;
Nuerobiology of Aging, Vol 27, Issue 2, Febm 2006,
Department of Psychiatry and Behavioral Sciences, BB-1520D Health Science Building, University of Washington, Box 356560, 1959 NE Pacific Street, Seattle, WA 98195-6560, USA

Memory

Growth hormone and memory, Jour Endocrinology, August 9 2010
Wass, A.H. and Reddy, Raghava

Growth hormone (GH) replacement unequivocally benefits growth, body composition, cardiovascular risk factors and quality of life. Less is known about the effects of GH on learning and memory. The recent paper on ‘early onset – GH deficiency (GHD) results in spatial memory impairment in mid life – and is prevented by GH supplementation’ by Nieves-Martinez importantly adds to this literature. Other data suggest that GH beneficially affects cognitive function in rats. In man, treatment of GHD has been associated with improvements in measures of memory and attention. There are also differences in verbal memory of patients with childhood onset GHD. Further questions remain, and the beneficial effects or otherwise of treating GHD in different age groups remain to be better defined. Certainly for reasons of maturation of neural connections and their development to young adulthood contemporaneous with rises in GH and IGF1 make these important areas for further study in man. Lastly because of what we already know in terms of cognitive effects of GHD, it is important to replace GH when studying other potential causes of adverse effects on cognition, for example, with radiotherapy.

Sleep

An Article Published In The Chicago Tribune News, Aug. 16, 2000, Summarized The Research on the Benefits Of Growth Hormone, Including Sleep

HGH Therapy is under the umbrella of AAG Health and Wellness, the world leaders in hormone management for adults. As the pioneers in treating adult hormone deficiencies to achieve optimal wellness, we are uniquely qualified to help adults of all ages regain a rich, fuller, and more satisfying quality of life. To find out if you are a candidate for growth hormone replacement therapy, please call us at (888) 877-4206 or complete the contact form and a representative will get back to you.

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